Discovery Challenges Belief About Brain’s Cellular Makeup

Discovery challenges belief about brain’s cellular makeup

A discovery made by Junhwan Kim, PhD, assistant professor at The Feinstein Institute for Medical Research, is challenging science’s longstanding beliefs regarding the cellular makeup of the brain. This breakthrough was outlined in a study published in the journal Molecular and Cellular Biochemistry. Having a full understanding of the brain can help identify new therapies as well as develop guidelines to maintain brain health.

It has long been a belief in the scientific field that the building blocks of brain cells, phospholipids, are enriched by polyunsaturated fatty acids. When trying to prove that the brain, like other major organs, are made of polyunsaturated fatty acids, Dr. Kim and his team were surprised by the results.

“We found the opposite of what science has widely believed – phospholipids containing polyunsaturated fatty acids in the brain are lower than other major organs,” said Dr. Kim. “Knowing that there are lower amounts of polyunsaturated fatty acids in the brain, we may need to rethink how this acid impacts brain health and conditions like oxygen deprivation.”

Dr. Kim and his team analyzed brain, heart, liver and kidney tissue from animals and found that only 60 percent of the brain’s phospholipids were made up of polyunsaturated fatty acids. That’s compared to other organs, where the polyunsaturated fatty acid content is about 90 percent. It has also been previously presumed that high polyunsaturated fatty acids levels in the brain were what made it susceptible to oxygen deprivation or brain injury. Further research is required to find out the reasoning for the difference in acid levels, but it could also challenge beliefs about polyunsaturated fatty acids’ impact on these conditions.

“Dr. Kim’s findings challenge basic assumptions about the brain,” said Kevin J. Tracey, MD, president and CEO of the Feinstein Institute. “This paper is an important step to defining a new research path.”

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March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico
March For Science, California State University, Chico

March for Science, California State University, Chico


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7 years ago

Brain patterns underlying mothers’ responses to infant cries

Infant cries activate specific brain regions related to movement and speech, according to a National Institutes of Health study of mothers in 11 countries. The findings, led by researchers at NIH’s Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), identify behaviors and underlying brain activities that are consistent among mothers from different cultures. Understanding these reactions may help in identifying and treating caregivers at risk for child maltreatment and other problematic behaviors.

Brain Patterns Underlying Mothers’ Responses To Infant Cries

The study team conducted a series of behavioral and brain imaging studies using functional magnetic resonance imaging (fMRI). In a group of 684 new mothers in Argentina, Belgium, Brazil, Cameroon, France, Israel, Italy, Japan, Kenya, South Korea and the United States, researchers observed and recorded one hour of interaction between the mothers and their 5-month-old babies at home. The team analyzed whether mothers responded to their baby’s cries by showing affection, distracting, nurturing (like feeding or diapering), picking up and holding, or talking. Regardless of which country they came from, mothers were likely to pick up and hold or talk to their crying infant.

Through fMRI studies of other groups of women, the team found that infant cries activated similar brain regions in new and experienced mothers: the supplementary motor area, which is associated with the intention to move and speak; the inferior frontal regions, which are involved in the production of speech; and the superior temporal regions that are linked to sound processing.

Overall, the findings suggest that mothers’ responses to infant cries are hard-wired and generalizable across cultures. The study also builds upon earlier work showing that women’s and men’s brains respond differently to infant cries.

7 years ago

At age 23, Tina Fey was working at a YMCA. At age 23, Oprah was fired from her first reporting job.  At age 24, Stephen King was working as a janitor and living in a trailer. 

At age 27, Vincent Van Gogh failed as a missionary and decided to go to art school.   At age 28, J.K. Rowling was a suicidal single parent living on welfare.

At age 28, Wayne Coyne ( from The Flaming Lips) was a fry cook. At age 30, Harrison Ford was a carpenter.  At age 30, Martha Stewart was a stockbroker.  At age 37, Ang Lee was a stay-at-home-dad working odd jobs. Julia Child released her first cookbook at age 39, and got her own cooking show at age 51. Vera Wang failed to make the Olympic figure skating team, didn’t get the Editor-in-Chief position at Vogue, and designed her first dress at age 40. Stan Lee didn’t release his first big comic book until he was 40. Alan Rickman gave up his graphic design career to pursue acting at age 42. Samuel L. Jackson didn’t get his first movie role until he was 46.

Morgan Freeman landed his first movie role at age 52. Kathryn Bigelow only reached international success when she made The Hurt Locker at age 57. Grandma Moses didn’t begin her painting career until age 76. Louise Bourgeois didn’t become a famous artist until she was 78. Whatever your dream is, it is not too late to achieve it. You aren’t a failure because you haven’t found fame and fortune by the age of 21. Hell, it’s okay if you don’t even know what your dream is yet. Even if you’re flipping burgers, waiting tables or answering phones today, you never know where you’ll end up tomorrow. Never tell yourself you’re too old to make it. 

Never tell yourself you missed your chance. 

Never tell yourself that you aren’t good enough. 

You can do it. Whatever it is. 

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