Hey Honest Question, Did Anybody Have GOOD Stuff Happen To Them In 2024? Cause It Was Really Bad For

“The world taught woman nothing skillful and then said her work was valueless. It permitted her no opinions and then said she did not know how to think. It forbade her to speak in public, and said the sex had no orators. It denied her the schools, and said the sex had no genius. It robbed her of every vestige of responsibility, and then called her weak. It taught her that every pleasure must come as a favor from men, and when to gain it she decked herself in paint and fine feathers, as she had been taught to do, it called her vain.”

-Carrie Chapman Catt, 1902

Solving violence against trans people seems to include the same solutions as solving violence against most other people: housing, safe spaces to go in uncertain times, gun regulations.

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Man withstands 800+ snake bites — on purpose — to find a universal anti-venom

Tim Friede’s blood is now the source of a potential new universal anti-venom, following hundreds of meticulous bites and venomous injections

"Tim Friede’s YouTube channel is home to a collection of videos depicting the Wisconsin-native truck mechanic subjecting himself to purposeful snake bites, blood slowly dripping down his arms.

For the past 20 years, Friede has been one of the most notorious “unconventional” medical researchers, undergoing over 200 bites from the world’s deadliest snakes — and more than four times as many — 850 — venomous injections. 

He did it all in the name of science.

According to the World Health Organization, an estimated 100,000 people are killed by snake bites each year, with countless more being disabled by the venom of the deadly reptiles. 

While life-saving anti-venom is available, very few countries actually have the capacity to produce it properly, given that most bites occur in remote and rural areas, and anti-venom requires arduous sourcing and accuracy. 

But Friede’s blood is now full of antibodies, following decades of strategic exposure to the neurotoxins of mambas, cobras, and other lethal slithering critters.

His blood is now the source material researchers are using to develop an anti-venom capable of neutralizing a broad spectrum of snake bites...

Friede started this hobby — which he is indeed adamant no one else tries at home — out of sheer curiosity in childhood. After playing with harmless garter snakes in his youth, he began keeping more dangerous species of snakes as pets. At one point, he had 60 of them in his home basement.

In 1999, he began extracting venom from his snakes, drying it, diluting it, and injecting himself with tiny doses — keeping meticulous records as he went.

He had one major hospitalization in 2001, when he was paralyzed and in a coma for four days. But instead of giving up, he doubled down. 

“In hindsight, I’m glad it happened,” Friede told The Times. “I never made another mistake.”

Jacob Glanville, an immunologist and founder of biotech company Centivax, stumbled on Friede’s videos.

Now, Friede is the director of herpetology at Centivax and serves as something of a “human lab” to Glanville.

“For a period of nearly 18 years, [Tim] had undertaken hundreds of bites and self-immunizations with escalating doses from 16 species of very lethal snakes that would normally a kill a horse,” Glanville told The Guardian.

“It blew my mind. I contacted him because I thought if anyone in the world has these properly neutralizing antibodies, it’s him.”

To develop the new anti-venom, Glanville and his fellow researchers identified 19 of the world’s deadliest snakes — in the elapid family — which kill their prey by injecting neurotoxins into their bloodstream, paralyzing muscles (including the big, important ones, like the heart and lungs).

The trouble is, each species in the elapid family has a slightly different toxin, meaning they would each require their own anti-venom.

But Friede’s blood contains certain fragments of each of these toxins; protein molecules seen across the various species. Because of his decades of service to science, his blood also contains the antibodies required to neutralize these toxins, preventing them from sticking to human cells and causing harm.

Combining the antibodies LNX-D09, SNX-B03, and a small molecule called varespladib that inhibits venom toxins, Centivax has successfully created a treatment effective against the entire range of 19 species’ toxins.

Their work, which was recently published in the journal Cell, will soon be tested outside of the lab. 

Trials will start with using the serum to treat dogs admitted to Australian veterinary clinics for snake bites. Assuming that goes well, the next step will be to administer human tests.

Researchers also believe that because the serum stems from a human, this should also lower the risk of allergic reactions when being administered to other people. 

“The final product would be a single, pan-anti-venom cocktail,” Professor Peter Kwong of Columbia University, a senior author of the study, told The Times.

Or, he added, they could make two: “One that is for the elapids, and another that is for the viperids, because some areas of the world only have one or the other.”

As for Friede, he maintains his affinity for snakes, though his last bite was in November 2018, when he said “enough is enough,” according to The New York Times.

By then, he had certainly done enough. His pursuit of immunity could feasibly save countless lives.

“I’m really proud that I can do something in life for humanity,” Friede told The New York Times, “to make a difference for people that are 8,000 miles away, that I’m never going to meet, never going to talk to, never going to see, probably.”

-via GoodGoodGood, May 2, 2025

New tin foil hat theory: the rise and propagation of minimalist home decor is meant to manage expectations for a desired culture of renters.

ppl on this website who don’t have sex irl will mention “missionary in the dark with your spouse” like it’s the worst most bland thing in existence. when rly thats just a fun cozy early morning activity. if u turn on the lights or i get up how am i supposed to fall back asleep after?? im more and more convinced that these people know nothing about a healthy sexual relationship. if you can’t enjoy ‘boring’ or vanilla sex i think you don’t like the person you’re fucking or you’re really bad at sex idfk

Can’t reblog the post going round containing these two screenshots:

So I’ll put my addition here:

This also applies to women who complain about feminism requiring them to work, rather than being ‘ladies of leisure’. Women equivalent to them in the past always worked - who do they think were the maids, housekeepers, cooks, nannies, wet nurses, governesses, washerwomen, spinners, weavers, seamstresses, nurses, midwives, etc - and today’s equivalent of the past’s ladies of leisure can afford to be ladies of leisure now. Feminism fought for women’s work to be acknowledged, valued, and fairly paid, and that fight is still ongoing.

I simply cannot take these men seriously, mostly because I have been big into fandom/fanfiction at various points in my life and alpha/beta/omega has a very different meaning in fandom terms 🤣🤣🤣

This is the conservative male version of neogenders. A bunch of weirdos got addicted to the internet and started calling themselves "omega males" as if that means something. It's their version of saying "I am a fem-aligned non-binary genderfuck who goes by he/she/its pronouns." It's amazing how different communities mirror each other even though they appear to be complete opposites at first glance.

This lasagna recipe is remarkable but OP is a terf

Hey, take it from someone creeping towards 40:

Ignore the fun police.

If you like it, order your steak well done. Get your bagel toasted with jam and butter. Put ice in your scotch and ketchup on your hotdog. Get red wine with fish and white with steak. Who cares?

If you want to, listen to pop music. Watch blockbuster popcorn flicks. Read dime store novels. Enjoy them.

Dye your hair or cut it off. Paint your fingernails blue. Wear whatever the fuck you want on your own time (ie, when not at a job or school or whatever where you can get penalized for breaking rules) as long as you aren’t like welding or shoveling snow.

Anyone who tries to tell you you’re wrong? Say “okay” and go back to what you were doing. You’re not hurting them by enjoying yourself or having things the way you like them.

There are no caveats or addendums to this. No “but what about x?” Nah. You’re allowed the things you like. You don’t have to justify your taste or apologize for it if it’s not hurting anyone.

And likewise, let other people live their lives. We’re all dead in the long run, so tend your own garden before you become fertilizer in it.

maybe the actual reason is that your conscience was trying to dissuade you from telling your girlfriend you want to cheat on her