Removing Troublemakers

A few rotten apples shouldn’t ruin the whole bunch. With millions of cells in the body, it’s inevitable that some will make a misstep and need to be quietly removed. Extrusion is one method for such a dismissal, when a rogue cell is squeezed out of a layer of cells with minimal disruption to its neighbours (pictured, centre pink cell being extruded from the green embryo of a microscopic worm). A new study investigated genetic activity linked to extrusion, and revealed that the process is triggered when cells falter in the midst of DNA replication and cell division. Such errors can prompt cancer development, so removing these cells might be an intrinsic cancer-prevention technique. Further experiments in human cells revealed the involvement of a well-known cancer suppressor protein called p53, showing the body aims to cull cancerous cells before they get going.

Written by Anthony Lewis

Image from work by Vivek K. Dwivedi and colleagues

Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA

Image copyright held by the original authors

Research published in Nature, May 2021

You can also follow BPoD on Instagram, Twitter and Facebook

More Posts from Polskapika and Others

polskapika

3 years ago

Made some Sunflora mousse cakes sprouting in chocolate pots 🌻💛

Made the Sunflora out of SunButter ganache, white chocolate, matcha Pocky, and buttercream, planted in chocolate pots filled with layers of chocolate cake, chocolate mousse, Oreos, and SunButter mousse, topped with "dirt" made out of Oreo crumbs and hot cocoa mix 🌱 So glad spring is here!

Tags

pokemon pokemon go food art nintendo cake pkmn homemade chocolate sunflower nerdy gen 2 sunflora Pokemon food pokemongo pokemon foodblog pokemon cake

993 notes View Post

polskapika

3 years ago

hex maniac art

6K notes View Post

polskapika

2 years ago

Little Miss Pokémon Trainer memes.

455 notes View Post

polskapika

1 week ago

Here Is My Old Notes On Ubiquitin From Biochemistry! Sorry For Any Misspelling Or Mistakes In Wording!

Here is my old notes on Ubiquitin from biochemistry! Sorry for any misspelling or mistakes in wording!

Tags

sorry for any mistakes biochemistry biochem notes ubiquitin biochemist undergraduate

0 notes View Post

polskapika

3 years ago

Been playing Legends Arceus all day since launch, and I’m so close to meeting god

Edit: I caught God

Tags

pokemon pokemon legends arceus pokemon fanart pokemon art Legends Arceus diamond and pearl

27K notes View Post

polskapika

3 weeks ago

Kate Moss by Mario Testino

2K notes View Post

polskapika

3 years ago

This implies he fucked her in the cow thingy

54K notes View Post

polskapika

2 years ago

440 notes View Post

polskapika

3 years ago

strawberry fields solangelo!!

Tags

my art art illustration artists on tumblr sketch drawing clip studio paint doodle digital artist solangelo pjo toa hoo heroes of olympus riordanverse trials of apollo will solace nico di angelo Percy Jackson and the olympians inspired by a maurice (1987) screencap i tried so hard with the background bye so happy with how will turned out:) yeah. really cute really sweet

2K notes View Post

polskapika

3 years ago